Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine

Base Information

• Chemical Name: Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine
• CAS No.: 144782-45-6
• Molecular Formula: C₁₇H₁₉NOS
• Molecular Weight: 285.41
• Mol file: 144782-45-6.mol

Synonyms:Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine

Chemical Property of Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine

There total 2 articles about Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(+)-(R)-1-(p-tolylsulfinyl)-2-propanone (66536-78-5) + benzylamine (100-46-9) → Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine (144782-45-6)

Guidance literature:

With 3 A molecular sieve; In benzene; for 12h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61167-X

Reference yield:

N-(isopropylidene)benzylamine (1197-48-4) + (-)-menthyl p-toluenesulfinate (1517-82-4) → Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine (144782-45-6)

Guidance literature:

With magnesium bromide; lithium diisopropyl amide; Yield given. Multistep reaction; 1) THF, -48 deg C, 15 min, 2) THF, room temp., 1 h;

DOI:10.1016/S0040-4039(00)61167-X

Reference yield: 80.0%

Benzyl-[1-methyl-2-((R)-toluene-4-sulfinyl)-eth-(E)-ylidene]-amine (144782-45-6) → (1R,(S)R)-N-benzyl-1-methyl-2-(p-tolylsulfinyl)ethylamine (144830-29-5)

Guidance literature:

With diisobutylaluminium hydride; zinc dibromide; at -22 ℃; for 3h; reduction with selectride; other chiral β-iminosulfoxides as substrates;

DOI:10.1016/S0040-4039(00)61167-X

upstream raw materials:

N-(isopropylidene)benzylamine

(-)-menthyl p-toluenesulfinate

(+)-(R)-1-(p-tolylsulfinyl)-2-propanone

benzylamine

Downstream raw materials:

Benzyl-[(S)-1-methyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

(1R,(S)R)-N-benzyl-1-methyl-2-(p-tolylsulfinyl)ethylamine