Technology Process of (E)-17-hexatriaconten-1-yl methanesulfonate
There total 1 articles about (E)-17-hexatriaconten-1-yl methanesulfonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 72 percent / HCl / diethyl ether / Ambient temperature
2: 1.) n-BuLi / 1.) RT, HMPT, hexane, 15 min, 2.) RT, 12 h
3: 93 percent / p-toluene sulfonic acid / ethanol / 2 h / Heating
4: 85 percent / LiAlH4 / bis-(2-hydroxy-ethyl) ether / 288 h / 125 °C
5: 95 percent / pyridine / CH2Cl2 / 72 h / Heating
With
pyridine; hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; toluene-4-sulfonic acid;
In
diethyl ether; ethanol; dichloromethane; diethylene glycol;
DOI:10.1021/jo00142a003
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91 percent / NaI / acetone / 24 h / Heating; in the dark
2: 1.) NaH, 2.) n-BuLi / 1.) THF, RT, 1 h, 2.) hexane, from 0 deg C to reflux, 1 h
3: 66 percent / NaBH4 / methanol; tetrahydrofuran / 0.5 h / Ambient temperature
4: 1.) KOH, 2.) ethyl diisopropylamine / 1.) methanol, benzene, reflux, 2 h, 2.) CHCl3, CH3CN, 50 deg C, 2 h
With
potassium hydroxide; sodium tetrahydroborate; n-butyllithium; sodium hydride; N-ethyl-N,N-diisopropylamine; sodium iodide;
In
tetrahydrofuran; methanol; acetone;
DOI:10.1021/jo00142a003
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91 percent / NaI / acetone / 24 h / Heating; in the dark
2: 1.) NaH, 2.) n-BuLi / 1.) THF, RT, 1 h, 2.) hexane, from 0 deg C to reflux, 1 h
3: 66 percent / NaBH4 / methanol; tetrahydrofuran / 0.5 h / Ambient temperature
4: 1.) KOH, 2.) ethyl diisopropylamine / 1.) methanol, benzene, reflux, 2 h, 2.) CHCl3, CH3CN, 50 deg C, 2 h
With
potassium hydroxide; sodium tetrahydroborate; n-butyllithium; sodium hydride; N-ethyl-N,N-diisopropylamine; sodium iodide;
In
tetrahydrofuran; methanol; acetone;
DOI:10.1021/jo00142a003