Cycloheptylidene-((S)-1-phenyl-ethyl)-amine

Base Information

• Chemical Name: Cycloheptylidene-((S)-1-phenyl-ethyl)-amine
• CAS No.: 135940-69-1
• Molecular Formula: C₁₅H₂₁N
• Molecular Weight: 215.338
• Mol file: 135940-69-1.mol

Synonyms:Cycloheptylidene-((S)-1-phenyl-ethyl)-amine

Chemical Property of Cycloheptylidene-((S)-1-phenyl-ethyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cycloheptylidene-((S)-1-phenyl-ethyl)-amine

There total 1 articles about Cycloheptylidene-((S)-1-phenyl-ethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(S)-1-phenyl-ethylamine (2627-86-3) + cycloheptanone (502-42-1) → Cycloheptylidene-((S)-1-phenyl-ethyl)-amine (135940-69-1)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 8h; Heating;

DOI:10.1002/ardp.19913240604

Reference yield: 80.0%

Cycloheptylidene-((S)-1-phenyl-ethyl)-amine (135940-69-1) → (αS)-(-)-N-(1-Phenylethyl)cycloheptanamin-Hydrochlorid (135940-92-0)

Guidance literature:

With hydrogen; nickel; In ethanol; at 35 ℃; for 240h; under 3750.3 Torr;

DOI:10.1002/ardp.19913240604

Reference yield:

Cycloheptylidene-((S)-1-phenyl-ethyl)-amine (135940-69-1) → Cycloheptylamine hydrochloride (69163-89-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / H₂ / Raney-Ni / ethanol / 240 h / 35 °C / 3750.3 Torr

2: 90 percent / H₂ / 10percent Pd/C / ethanol / 48 h / 50 °C / 3750.3 Torr

With hydrogen; palladium on activated charcoal; nickel; In ethanol;

DOI:10.1002/ardp.19913240604

upstream raw materials:

(S)-1-phenyl-ethylamine

cycloheptanone

Downstream raw materials:

(αS)-(-)-N-(1-Phenylethyl)cycloheptanamin-Hydrochlorid

Cycloheptylamine hydrochloride