Propiomazine

Base Information

• Chemical Name: Propiomazine
• CAS No.: 362-29-8
• Molecular Formula: C₂₀H₂₄N₂OS
• Molecular Weight: 340.489
• European Community (EC) Number: 206-646-1
• UNII: 242Z0PM79Y
• DSSTox Substance ID: DTXSID1023520
• Nikkaji Number: J5.699E
• Wikipedia: Propiomazine
• Wikidata: Q7250328
• NCI Thesaurus Code: C66486
• Pharos Ligand ID: 28GQPJBXNSC9
• Metabolomics Workbench ID: 43072
• ChEMBL ID: CHEMBL1201210
• Mol file: 362-29-8.mol

Synonyms:Largon;propiomazine

Chemical Property of Propiomazine

Chemical Property:

• Boiling Point: 500.8°Cat760mmHg
• PKA: pKa 6.6(H2O) (Uncertain)
• Flash Point: 256.7°C
• PSA: 48.85000
• Density: 1.137g/cm³
• LogP: 4.89710
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 340.16093457
• Heavy Atom Count: 24
• Complexity: 441

Purity/Quality:

99.9% ^*data from raw suppliers

1-[10-[2-(Dimethylamino)propyl]phenothiazin-2-yl-1-propanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CC(C)N(C)C
• Uses: Propiomazine is used in the preparation of analgesics as well as maintaining its own analgesic effects whilst applied to various neurological diseases. 1-[10-[2-(Dimethylamino)propyl]phenothiazin-2-yl-1-propanone is used in the preparation of analgesics as well as maintaining its own analgesic effects whilst applied to various neurological diseases.

Technology Process of Propiomazine

There total 4 articles about Propiomazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-propionyl-phenothiazine-10-carbonyl chloride (92853-69-5) → propiomazine (362-29-8,118205-97-3,118205-98-4)

Guidance literature:

Erhitzen des Reaktionsprodukts;

Reference yield:

2-propionyl-phenothiazine-10-carbonyl chloride (92853-69-5) → propiomazine (362-29-8,118205-97-3,118205-98-4)

Guidance literature:

Erhitzen des Reaktionsprodukts;

Reference yield:

→ propiomazine (362-29-8,118205-97-3,118205-98-4)

Guidance literature:

3-Propionyl-phenothiazin-10-carbonsaeure-(2-dimethylamino-propylester) ;

upstream raw materials:

2-propionyl-phenothiazine-10-carbonyl chloride