methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose

Base Information

• Chemical Name: methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose
• CAS No.: 198338-70-4
• Molecular Formula: C₂₈H₃₂O₆
• Molecular Weight: 464.558
• Mol file: 198338-70-4.mol

Synonyms:methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose

Chemical Property of methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose

There total 6 articles about methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 6-O-allyl-2,3,5-tri-O-benzyl-α-D-mannofuranoside (246162-57-2) → methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose (198338-70-4)

Guidance literature:

palladium dichloride; In methanol; at 20 ℃; for 5h;

DOI:10.1080/07328309908544035

Reference yield:

1,2-anhydro-6-O-allyl-3,5-di-O-benzyl-β-D-mannofuranose (246162-55-0) → methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose (198338-70-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / 1 h

2: 95 percent / NaH / dimethylformamide / 5 h / 20 °C

3: 78 percent / PdCl₂ / methanol / 5 h / 20 °C

With sodium hydride; palladium dichloride; In methanol; N,N-dimethyl-formamide; 1: Ring cleavage / 2: Substitution / 3: Substitution;

DOI:10.1080/07328309908544035

Reference yield:

methyl 6-O-allyl-3,5-di-O-benzyl-α-D-mannofuranoside (246162-56-1) → methyl 2,3,5-tri-O-benzyl-α-D-mannofuranose (198338-70-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / NaH / dimethylformamide / 5 h / 20 °C

2: 78 percent / PdCl₂ / methanol / 5 h / 20 °C

With sodium hydride; palladium dichloride; In methanol; N,N-dimethyl-formamide; 1: Substitution / 2: Substitution;

DOI:10.1080/07328309908544035

upstream raw materials:

methyl 6-O-allyl-2,3,5-tri-O-benzyl-α-D-mannofuranoside

1,2-anhydro-6-O-allyl-3,5-di-O-benzyl-β-D-mannofuranose

methyl 6-O-allyl-3,5-di-O-benzyl-α-D-mannofuranoside