N-(Cycloheptylcarbonyl)-D-phenylalanine

Base Information

Chemical Name:N-(Cycloheptylcarbonyl)-D-phenylalanine
CAS No.:115732-16-6
Molecular Formula:C₁₇H₂₃NO₃
Molecular Weight:289.375
Hs Code.:
ChEMBL ID:CHEMBL285741
DSSTox Substance ID:DTXSID701280466

Synonyms:N-(Cycloheptylcarbonyl)-D-phenylalanine;CHEMBL285741;DTXSID701280466;AKOS025635185;115732-16-6

Suppliers and Price of N-(Cycloheptylcarbonyl)-D-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-(Cycloheptylcarbonyl)-D-phenylalanine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:289.16779360
Heavy Atom Count:21
Complexity:342

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCCC(CC1)C(=O)NC(CC2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1CCCC(CC1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)O

Technology Process of N-(Cycloheptylcarbonyl)-D-phenylalanine

There total 4 articles about N-(Cycloheptylcarbonyl)-D-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 6557-86-4
cycloheptanecarbonyl chloride

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 115732-16-6
N-(cycloheptylcarbonyl)-D-phenylalnine

Guidance literature:: With sodium hydroxide; In acetone;
DOI:10.1021/jm00119a007

Reference yield:

: N-(Cycloheptylcarbonyl)-D-phenylalanine methyl ester

: 115732-16-6
N-(cycloheptylcarbonyl)-D-phenylalnine

Guidance literature:: With sodium hydroxide; In methanol; Yield given;
DOI:10.1021/jm00127a006

Reference yield:

: 1460-16-8
cycloheptanoic acid

: 115732-16-6
N-(cycloheptylcarbonyl)-D-phenylalnine

Guidance literature:: Multi-step reaction with 2 steps

1: 1) N-hydroxysuccinimide, dicyclohexylcarbodiimide / 1) CHCl₃, 3 h, 2) CHCl₃, 25 deg C, 1 d

2: 2N NaOH / methanol

With sodium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In methanol;
DOI:10.1021/jm00127a006