5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

Base Information

Chemical Name:5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate
CAS No.:1039433-71-0
Molecular Formula:C₄₄H₄₀FNO₇
Molecular Weight:713.803
Hs Code.:

5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

Synonyms:5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

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Chemical Property of 5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

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Technology Process of 5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

There total 1 articles about 5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1039433-70-9
5-({4-[(2S,3R)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxo-1-(4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)azetidin-2-yl]phenyl}ethynyl)-2,2-dimethyl-1,3-dioxan-5-yl acetate

: 4039-82-1
Benzyl propargyl ether

: 1039433-71-0
5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

Guidance literature:: With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 70 ℃; for 5.05h;

Reference yield:

: 1039433-71-0
5-[(4-{(2S,3R)-1-{4-[3-(benzyloxy)prop-1-yn-1-yl]phenyl}-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl)ethynyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

: 1039433-72-1
5-[2-(4-{(2S,3R)-3-[3-(4-fluorophenyl)-3-oxopropyl]-1-[4-(3-hydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)ethyl]-2,2-dimethyl-1,3-dioxan-5-yl acetate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; palladium(II) hydroxide/carbon; In ethanol; at 20 ℃; for 4h; under 760.051 Torr;