4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester

Base Information

• Chemical Name: 4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester
• CAS No.: 1336896-08-2
• Molecular Formula: C₄₀H₄₃F₅N₆O₁₀S
• Molecular Weight: 894.874
• Mol file: 1336896-08-2.mol

Synonyms:4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester

Chemical Property of 4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester

Chemical Property:

Purity/Quality:

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Useful:

Technology Process of 4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester

There total 1 articles about 4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C34H44N6O10S (343776-74-9) + 2,3,4,5,6-pentafluorophenol (771-61-9) → 4-[4-[[(1R)-1-[[4-(1,2,4-oxadiazol-5(2H)-one)-phenyl]methyl]-2-oxo-2-(1-piperidinyl) ethyl]amino]-3-[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]-1,4(S)-dioxobutyl] amino-butanoic acid pentafluorophenyl ester (1336896-08-2)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/jlcr.1900

upstream raw materials:

C₃₄H₄₄N₆O₁₀S

2,3,4,5,6-pentafluorophenol