<1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine

Base Information

• Chemical Name: <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine
• CAS No.: 110567-27-6
• Molecular Formula: C₂₀H₂₄FNO₂
• Molecular Weight: 329.414
• Mol file: 110567-27-6.mol

Synonyms:<1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine

Chemical Property of <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine

There total 2 articles about <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H22FN3O2 (110567-25-4) → <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine (110567-27-6)

Guidance literature:

With hydrogen; Lindlar's catalyst; for 3.5h; under 760 Torr; Yield given;

DOI:10.1021/jm00163a030

Reference yield:

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol (110567-23-2) → <1R-(1α,2β,3α,4β)>-5-fluoro-3-(phenylmethoxy)-2-<(phenylmethoxy)methyl>-1-cyclopentanamine (110567-27-6) + <1S-(1α,2β,3α,4β)>-2-fluoro-4-(phenylmethoxy)-3-<(phenylmethoxy)methyl>-1-cyclopentanamine (110567-26-5)

Guidance literature:

With diethylamino-sulfur trifluoride; hydrogen; Lindlar catalyst; Multistep reaction; 1.) CH₂Cl₂;

DOI:10.1039/C39870000255

upstream raw materials:

C₂₀H₂₂FN₃O₂

(1S,2S,3S,5S)-5-azido-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol