(3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane

Base Information

• Chemical Name: (3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane
• CAS No.: 1190597-35-3
• Molecular Formula: C₁₈H₃₁BrO₂Si
• Molecular Weight: 387.432
• Mol file: 1190597-35-3.mol

Synonyms:(3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane

Chemical Property of (3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane

There total 1 articles about (3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2-methoxy-6-methyl-3-(triisopropylsilyloxy)phenyl)methanol (1190597-34-2) → (3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane (1190597-35-3)

Guidance literature:

(2-methoxy-6-methyl-3-(triisopropylsilyloxy)phenyl)methanol; With methanesulfonyl chloride; triethylamine; In dichloromethane; at -20 ℃; for 0.75h; Inert atmosphere;

With lithium bromide; In tetrahydrofuran; dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja906335u

Reference yield: 65.0%

(3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane (1190597-35-3) + essigsaeure-<(E,E,10S)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadien-1-yl>ester (93861-36-0) → (3-((3E,7E)-10-((S)-3,3-dimethyloxiran-2-yl)-4,8-dimethyldeca-3,7-dienyl)-2-methoxy-4-methylphenoxy)triisopropylsilane (1190597-36-4)

Guidance literature:

(3-(bromomethyl)-2-methoxy-4-methylphenoxy)triisopropylsilane; With magnesium; ethylene dibromide; In diethyl ether; for 1h; Reflux;

essigsaeure-<(E,E,10S)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadien-1-yl>ester; With dilithium tetrachlorocuprate; In tetrahydrofuran; diethyl ether; at 0 ℃; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ja906335u

upstream raw materials:

(2-methoxy-6-methyl-3-(triisopropylsilyloxy)phenyl)methanol

Downstream raw materials:

(3-((3E,7E)-10-((S)-3,3-dimethyloxiran-2-yl)-4,8-dimethyldeca-3,7-dienyl)-2-methoxy-4-methylphenoxy)triisopropylsilane