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3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate

Base Information Edit
  • Chemical Name:3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate
  • CAS No.:17736-20-8
  • Molecular Formula:C23H34 O6
  • Molecular Weight:406.519
  • Hs Code.:
  • European Community (EC) Number:241-728-0
  • NSC Number:87520,11575
  • DSSTox Substance ID:DTXSID10938926
  • Nikkaji Number:J287.139D
  • Wikidata:Q82915348
  • ChEMBL ID:CHEMBL3138721
  • Mol file:17736-20-8.mol
3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate

Synonyms:17736-20-8;3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate;Tetrahydrocortisone 21-acetate;TETRAHYDROCORTISONE ACETATE;EINECS 241-728-0;NSC 11575;NSC 87520;[2-[(3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-11-oxo-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;L 510844-0;MLS002638216;5.alpha.-Pregnane-3.beta.,21-triol-11,20-dione 21-acetate;5.beta.-Pregnan-3.alpha.,21-triol-11,20-dione 21-acetate;5beta-Pregnan-3alpha,17,21-triol-11,20-dione 21-acetate;Pregnane-11, 21-(acetyloxy)-3,17-dihydroxy-, (3.alpha.,5.beta.)-;NSC11575;SCHEMBL7978562;CHEMBL3138721;DTXSID10938926;NSC87520;NSC-11575;NSC-87520;HY-148379;CS-0620850;3,17-dihydroxy-11,20-dioxopregnan-21-yl acetate;21-(Acetyloxy)-3alpha,17alpha-dihydroxy-5beta-pregnane-11,20-dione;Pregnane-11,20-dione, 21-(acetyloxy)-3,17-dihydroxy-, (3.alpha.,5.beta.)-

Suppliers and Price of 3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • TETRAHYDROCORTISONE ACETATE 95.00%
  • 5MG
  • $ 450.37
Total 8 raw suppliers
Chemical Property of 3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate Edit
Chemical Property:
  • Vapor Pressure:9.97E-15mmHg at 25°C 
  • Boiling Point:557°Cat760mmHg 
  • Flash Point:187.4°C 
  • PSA:100.90000 
  • Density:1.228g/cm3 
  • LogP:2.43230 
  • XLogP3:2.2
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:4
  • Exact Mass:406.23553880
  • Heavy Atom Count:29
  • Complexity:733
Purity/Quality:

99% *data from raw suppliers

TETRAHYDROCORTISONE ACETATE 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4C3(CCC(C4)O)C)C)O
  • Isomeric SMILES:CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C)O
  • Uses 5β-Pregnan-3α,17α,21-triol-11,20-dion-21-acetate is a steroidal derivative used in the preparation of cortisone derivatives.
Technology Process of 3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate

There total 17 articles about 3alpha,17,21-Trihydroxy-5beta-pregnane-11,20-dione 21-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; at 0 ℃; for 2h; Reagent/catalyst; Solvent; Temperature; stereoselective reaction; Inert atmosphere;
DOI:10.1080/07328303.2021.2023559
Guidance literature:
With bromine; folgende Umsetzung mit Kaliumacetat;
DOI:10.1021/ja01135a039
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