6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

Base Information

Chemical Name:6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester
CAS No.:1256591-50-0
Molecular Formula:C₂₂H₁₅F₃N₂O₅
Molecular Weight:444.367
Hs Code.:

Synonyms:6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

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Chemical Property of 6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

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Technology Process of 6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

There total 2 articles about 6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 828-27-3
4-Trifluoromethoxyphenol

: 1256591-49-7
2-chloro-6-(4-cyano phenoxy)nicotinic acid ethyl ester

: 1256591-50-0
6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

Reference yield:

: 767-00-0
4-cyanophenol

: 58584-86-4
ethyl 2,6-dichloronicotinate

: 1256591-50-0
6-(4-cyano phenoxy)-2-(4-trifluoromethoxy phenoxy)nicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C

With potassium carbonate; In N,N-dimethyl-formamide;