(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

Base Information

Chemical Name:(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine
CAS No.:1353883-03-0
Molecular Formula:C₂₃H₁₆ClF₃N₂
Molecular Weight:412.842
Hs Code.:

Synonyms:(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

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Technology Process of (Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

There total 3 articles about (Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1353882-74-2
N-benzyl-N'-(2-((4-chlorophenyl)ethynyl)phenyl)-2,2,2-trifluoroacetimidamide

: 1353883-03-0
(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

Guidance literature:: With sodium tetrachloroaurate(III) dihyrate; In toluene; at 20 ℃; for 1h;
DOI:10.1039/c1ob06528a

Reference yield:

: 221910-19-6
2-(4-chlorophenylethynyl)phenylamine

: 1353883-03-0
(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrachloromethane; triethylamine; triphenylphosphine / 80 °C

2: triethylamine / N,N-dimethyl-formamide / 2 h / 80 °C

3: sodium tetrachloroaurate(III) dihyrate / toluene / 1 h / 20 °C

With tetrachloromethane; sodium tetrachloroaurate(III) dihyrate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; toluene;
DOI:10.1039/c1ob06528a

Reference yield:

: 1353883-57-4
C₁₆H₈Cl₂F₃N

: 100-46-9
benzylamine

: 1353883-03-0
(Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide / 2 h / 80 °C

2: sodium tetrachloroaurate(III) dihyrate / toluene / 1 h / 20 °C

With sodium tetrachloroaurate(III) dihyrate; triethylamine; In N,N-dimethyl-formamide; toluene;
DOI:10.1039/c1ob06528a