C₂₁H₂₁Cl₆N₇O₁₀S

Base Information

Chemical Name:C₂₁H₂₁Cl₆N₇O₁₀S
CAS No.:1254691-11-6
Molecular Formula:C₂₁H₂₁Cl₆N₇O₁₀S
Molecular Weight:776.223
Hs Code.:

C<sub>21</sub>H<sub>21</sub>Cl<sub>6</sub>N<sub>7</sub>O<sub>10</sub>S

Synonyms:C₂₁H₂₁Cl₆N₇O₁₀S

Suppliers and Price of C₂₁H₂₁Cl₆N₇O₁₀S

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₁H₂₁Cl₆N₇O₁₀S

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₁H₂₁Cl₆N₇O₁₀S

There total 10 articles about C₂₁H₂₁Cl₆N₇O₁₀S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1061574-09-1
C₂₁H₂₁Cl₆N₇O₉S

: 1254691-11-6
C₂₁H₂₁Cl₆N₇O₁₀S

Guidance literature:: With Dess-Martin periodane; In dichloromethane; for 0.333333h;

Reference yield:

: 1061574-16-0
C₂₈H₃₃Cl₃N₄O₅S₂Si

: 1254691-11-6
C₂₁H₂₁Cl₆N₇O₁₀S

Guidance literature:: Multi-step reaction with 10 steps

1.1: 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 29 h / 37 °C / Inert atmosphere; Sealed tube

2.1: ammonia / methanol / 24 h / 70 °C / Inert atmosphere; Sealed tube

3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / -20 °C / Inert atmosphere

4.1: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; magnesium oxide / dichloromethane / 2.5 h / 42 °C / Inert atmosphere; Sealed tube

5.1: boron trifluoride diethyl etherate; triethylsilane / dichloromethane / 1.5 h / -78 - 20 °C / Inert atmosphere

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / -78 - 0 °C / Inert atmosphere

7.1: dichloromethane / 0.25 h / -20 °C / Inert atmosphere

7.2: 12 h / Inert atmosphere

8.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; tetrahydrofuran / 12 h / Inert atmosphere

9.1: dmap / dichloromethane; acetonitrile / 1.5 h / -78 °C / Inert atmosphere

10.1: Dess-Martin periodane / dichloromethane / 0.33 h / Inert atmosphere

With triethylsilane; dmap; osmium(VIII) oxide; bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; ammonia; magnesium oxide; Dess-Martin periodane; 4-methylmorpholine N-oxide; N-ethyl-N,N-diisopropylamine; 2,4,6-tri-tert-butylpyrimidine; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/jacs.6b02343

Reference yield:

: 1061574-11-5
C₉H₁₂N₂O₄

: 1254691-11-6
C₂₁H₂₁Cl₆N₇O₁₀S

Guidance literature:: Multi-step reaction with 14 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 14 h / 0 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / dichloromethane; toluene / 2 h / -90 °C / Inert atmosphere

3.1: dichloromethane / 0.33 h / 0 - 20 °C / Inert atmosphere

3.2: 1.67 h / -78 - 20 °C / Inert atmosphere

4.1: 1,3-dimethylbarbituric acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / dichloromethane / 8 h / Inert atmosphere

4.2: 0.33 h / Inert atmosphere

5.1: 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 29 h / 37 °C / Inert atmosphere; Sealed tube

6.1: ammonia / methanol / 24 h / 70 °C / Inert atmosphere; Sealed tube

7.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / -20 °C / Inert atmosphere

8.1: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; magnesium oxide / dichloromethane / 2.5 h / 42 °C / Inert atmosphere; Sealed tube

9.1: boron trifluoride diethyl etherate; triethylsilane / dichloromethane / 1.5 h / -78 - 20 °C / Inert atmosphere

10.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / -78 - 0 °C / Inert atmosphere

11.1: dichloromethane / 0.25 h / -20 °C / Inert atmosphere

11.2: 12 h / Inert atmosphere

12.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; tetrahydrofuran / 12 h / Inert atmosphere

13.1: dmap / dichloromethane; acetonitrile / 1.5 h / -78 °C / Inert atmosphere

14.1: Dess-Martin periodane / dichloromethane / 0.33 h / Inert atmosphere

With 1H-imidazole; triethylsilane; dmap; osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid; bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; ammonia; magnesium oxide; diisobutylaluminium hydride; Dess-Martin periodane; 4-methylmorpholine N-oxide; N-ethyl-N,N-diisopropylamine; 2,4,6-tri-tert-butylpyrimidine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile; 3.1: |Pictet-Spengler Synthesis / 3.2: |Pictet-Spengler Synthesis;
DOI:10.1021/jacs.6b02343