(2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Base Information

Chemical Name:(2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
CAS No.:92131-78-7
Molecular Formula:C₄₂H₈₁NO₁₁
Molecular Weight:776.105
Hs Code.:
DSSTox Substance ID:DTXSID70919357

Synonyms:1,2-di-O-tetradecyl-3-O-alpha-sialyl-sn-glycerol;1,2-di-O-tetradecyl-3-O-alpha-sialylglycerol;DTSL

Suppliers and Price of (2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of (2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:884.8°Cat760mmHg
Flash Point:488.9°C
Density:1.09g/cm³
XLogP3:10.2
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:37
Exact Mass:775.58096240
Heavy Atom Count:54
Complexity:912

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCCCCCCCCCCOCC(COC1(CC(C(C(O1)C(C(CO)O)O)NC(=O)C)O)C(=O)O)OCCCCCCCCCCCCCC
Isomeric SMILES:CCCCCCCCCCCCCCOC[C@H](CO[C@@]1(C[C@@H](C([C@@H](O1)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)OCCCCCCCCCCCCCC

Technology Process of (2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

There total 8 articles about (2R,4S,6R)-5-acetamido-2-[(2R)-2,3-di(tetradecoxy)propoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92131-77-6,92131-80-1,115794-29-1
(2S,4S,5R,6R)-5-Acetylamino-2-((R)-2,3-bis-tetradecyloxy-propoxy)-4-hydroxy-6-((1S,2S)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester

: 92131-78-7,92131-79-8,113725-44-3,113725-45-4
(2S,4S,5R,6R)-5-Acetylamino-2-((R)-2,3-bis-tetradecyloxy-propoxy)-4-hydroxy-6-((1S,2S)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; Yield given;
DOI:10.1016/0008-6215(84)85097-1

Reference yield:

: 92131-77-6,92131-80-1,115794-29-1
(2R,4S,5R,6R)-5-Acetylamino-2-((R)-2,3-bis-tetradecyloxy-propoxy)-4-hydroxy-6-((1S,2S)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester

: 92131-78-7,92131-79-8,113725-44-3,113725-45-4
(2R,4S,5R,6R)-5-Acetylamino-2-((R)-2,3-bis-tetradecyloxy-propoxy)-4-hydroxy-6-((1S,2S)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; Yield given;
DOI:10.1016/0008-6215(84)85097-1

Reference yield:

: 1070-07-1
(S)-1,2-bis-tetradecyloxy propane-3-ol

: 92131-78-7,92131-79-8,113725-44-3,113725-45-4
(2S,4S,5R,6R)-5-Acetylamino-2-((R)-2,3-bis-tetradecyloxy-propoxy)-4-hydroxy-6-((1S,2S)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 24 percent / Hg(CN)2, HgBr₂ / CH₂Cl₂ / 48 h / 20 °C

2: NaOMe / methanol

3: 0.1M NaOH / tetrahydrofuran

With sodium hydroxide; sodium methylate; mercury(II) cyanide; mercury dibromide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/0008-6215(84)85097-1