Methyldopa pivaloyloxyethyl ester

Base Information

Chemical Name:Methyldopa pivaloyloxyethyl ester
CAS No.:81660-38-0
Molecular Formula:C17H25NO6
Molecular Weight:339.389
Hs Code.:
European Community (EC) Number:279-793-2
UNII:WBI8SO7K59
DSSTox Substance ID:DTXSID301002119
Nikkaji Number:J296.102D
Mol file:81660-38-0.mol

Synonyms:methyldopa pivaloyloxyethyl ester;methyldopa pivaloyloxyethyl ester hydrochloride;pivaloyloxyethyl methyldopa ester;POE methyldopa

Suppliers and Price of Methyldopa pivaloyloxyethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Methyldopa pivaloyloxyethyl ester

Chemical Property:

PSA：119.08000
LogP:2.53650
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:339.16818752
Heavy Atom Count:24
Complexity:461

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(OC(=O)C(C)(C)C)OC(=O)C(C)(CC1=CC(=C(C=C1)O)O)N
Isomeric SMILES:CC(OC(=O)[C@](C)(CC1=CC(=C(C=C1)O)O)N)OC(=O)C(C)(C)C

Technology Process of Methyldopa pivaloyloxyethyl ester

There total 3 articles about Methyldopa pivaloyloxyethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.8%

R,S-1-pivaloyloxyethyl S-3-(3,4-dihydroxy-phenyl)-2-methylalaninate, phosphoric acid salt: R,S-1-pivaloyloxyethyl S-3-(3,4-dihydroxy-phenyl)-2-methylalaninate, phosphoric acid salt

: 81660-38-0
α-pivaloyloxyethyl (S)-3-(3,4-dihydroxyphenyl)-2-methylalaninate

Guidance literature:

Reference yield:

: 81660-38-0
α-pivaloyloxyethyl (S)-3-(3,4-dihydroxyphenyl)-2-methylalaninate

Guidance literature:

Reference yield:

: 40258-80-8
1-chloroethyl pivalate

: 55-40-3,555-29-3,88620-56-8
alpha-methyldopa

: 81660-38-0
α-methyldopa pivaloylethyl ester

: 102108-09-8
3-(3,4-Dihydroxy-phenyl)-2-[1-(2,2-dimethyl-propionyloxy)-ethylamino]-2-methyl-propionic acid 1-(2,2-dimethyl-propionyloxy)-ethyl ester

Guidance literature:: With 4 A molecular sieve; In various solvent(s); at 75 ℃; for 8h; Product distribution; other temperature, various solvents; other alkylating agents; other amino acids; with or without LiBr;
DOI:10.1021/jo00363a033