(2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide

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Chemical Name:(2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide
CAS No.:361483-73-0
Molecular Formula:C₂₆H₃₉N₃O₂
Molecular Weight:425.615
Hs Code.:

Synonyms:(2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide

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Chemical Property of (2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide

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Technology Process of (2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide

There total 1 articles about (2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 134860-26-7
1-<(S)-1-Phenylethyl>-2,5-(S,S)-bis(methoxycarbonyl)pyrrolidine

: 361483-73-0
(2S,5S)-1-[(S)-1-phenylethyl]-pyrrolidine-2,5-dicarboxylic acid bis-cyclohexylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / aq. NaOH / methanol / 10 h / Heating

2: 61 percent / HOBt; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylformamide / 20 °C

With sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/ol016260i