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Technology Process of Dechloro perphenazine

Dechloro perphenazine

Base Information
  • Chemical Name:Dechloro perphenazine
  • CAS No.:3533-97-9
  • Molecular Formula:C21H27N3OS
  • Molecular Weight:369.52
  • Hs Code.:2934990002
  • UNII:725URK91YR
  • Wikidata:Q27266023
  • Mol file:3533-97-9.mol
Dechloro perphenazine

Synonyms:Dechloro perphenazine;3533-97-9;Phenazine (pharmaceutical);2-[4-(3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethanol;UNII-725URK91YR;725URK91YR;Perphenazine specified impurity B [EP];1-Piperazineethanol, 4-(3-(10H-phenothiazin-10-yl)propyl)-;2-(4-(3-(10H-Phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol;2-[4-[3-(10H-Phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol;2-(4-(3-(10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-ol;CBDivE_006095;1-Piperazineethanol, 4-[3-(10H-phenothiazin-10-yl)propyl]-;PERPHENAZINE IMPURITY B [EP IMPURITY];A899631;Q27266023;1-Piperazineethanol, 4-(3-phenothiazin-10-ylpropyl)-

Suppliers and Price of Dechloro perphenazine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 4-(3-Phenothiazin-10-ylpropyl)-1-piperazineethanol
  • 1g
  • $ 1390.00
  • Medical Isotopes, Inc.
  • 4-(3-Phenothiazin-10-ylpropyl)-1-piperazineethanol
  • 1 g
  • $ 2200.00
Total 10 raw suppliers
Chemical Property of Dechloro perphenazine
Chemical Property:
  • Melting Point:95-97°C 
  • Storage Temp.:Refrigerator 
  • Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) 
  • XLogP3:3.6
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:6
  • Exact Mass:369.18748367
  • Heavy Atom Count:26
  • Complexity:408
Purity/Quality:

97% *data from raw suppliers

4-(3-Phenothiazin-10-ylpropyl)-1-piperazineethanol *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CN(CCN1CCCN2C3=CC=CC=C3SC4=CC=CC=C42)CCO
  • Uses 4-(3-Phenothiazin-10-ylpropyl)-1-piperazineethanol (Perphenazine EP Impurity B; Perphenazine USP Related Compound B) is the dechlorinated analogue of Perphenazine (P291100), an D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist.
Technology Process of Dechloro perphenazine

There total 1 articles about Dechloro perphenazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-(3-<4-(2-Hydroxy-aethyl)-piperazino>-propyl)-phenthiazin.
3533-97-9

10-(3-<4-(2-Hydroxy-aethyl)-piperazino>-propyl)-phenthiazin.

Guidance literature:
Phenthiazin, NaOH in sied. Toluol (30 min), 1-(3-Chlor-propyl)-4-(2-hydroxy-aethyl)-piperazin-dihydrochlorid, (Siedetemp. 6 h.).;
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