2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide

Base Information

• Chemical Name: 2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide
• CAS No.: 1208328-29-3
• Molecular Formula: C₂₃H₁₇F₃N₂OS
• Molecular Weight: 426.462

Synonyms:2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide

Chemical Property of 2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

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Technology Process of 2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide

There total 1 articles about 2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

benzothiophene-3-carboxaldehyde (5381-20-4) + 2-amino N-[3-(trifluoromethyl)phenyl]benzamide (20878-52-8) → 2-(benzo[b]thiophen-3-ylmethylamino)-N-[3-(trifluoromethyl)-phenyl]benzamide (1208328-29-3)

Guidance literature:

benzothiophene-3-carboxaldehyde; 2-amino N-[3-(trifluoromethyl)phenyl]benzamide; With acetic acid; In methanol; at 23 ℃; for 8h; Inert atmosphere;

With sodium cyanoborohydride; In methanol; at 23 ℃; for 24h; Inert atmosphere;

DOI:10.1002/cmdc.200900373

upstream raw materials:

benzothiophene-3-carboxaldehyde

2-amino N-[3-(trifluoromethyl)phenyl]benzamide

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