N-benzyl-2-aza-[3]-ferrocenophane

Base Information

• Chemical Name: N-benzyl-2-aza-[3]-ferrocenophane
• CAS No.: 244272-22-8
• Molecular Formula: C₁₉H₁₉FeN
• Molecular Weight: 317.214
• Mol file: 244272-22-8.mol

Synonyms:N-benzyl-2-aza-[3]-ferrocenophane

Chemical Property of N-benzyl-2-aza-[3]-ferrocenophane

Chemical Property:

Purity/Quality:

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Technology Process of N-benzyl-2-aza-[3]-ferrocenophane

There total 3 articles about N-benzyl-2-aza-[3]-ferrocenophane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,1'-ferrocenyldicarboxaldehyde (1271-48-3) + benzylamine (100-46-9) → N-benzyl-2-aza-[3]-ferrocenophane (244272-22-8)

Guidance literature:

1,1'-ferrocenyldicarboxaldehyde; benzylamine; In dichloromethane; at 20 ℃; for 1h; Schlenk technique; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1021/om400317s

Reference yield: 70.0%

1,1'-dihydroxymethylferrocene + benzylamine (100-46-9) → N-benzyl-2-aza-[3]-ferrocenophane (244272-22-8)

Guidance literature:

tris(triphenylphosphine)ruthenium(II) chloride; In not given; in NMA solvent (N-methylpyrrolidinone ?); N2-atmosphere, equimolar amts., 180°C, 24 h, then room temp. overnight; chromy. (SiO2, AcOEt/hexane=1:1); elem. anal.;

DOI:10.1016/S0022-328X(99)00114-X

Reference yield:

C19H17FeNO → N-benzyl-2-aza-[3]-ferrocenophane (244272-22-8)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/aoc.2839

upstream raw materials:

benzylamine

1,1'-ferrocenyldicarboxaldehyde