N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride

Base Information

• Chemical Name: N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride
• CAS No.: 105363-12-0
• Molecular Formula: C₉H₁₀ClNO₃
• Molecular Weight: 215.636
• Mol file: 105363-12-0.mol

Synonyms:N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride

Chemical Property of N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride

There total 4 articles about N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3,4-Dimethoxy-benzaldehyde oxime (2169-98-4,39627-82-2) → N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride (105363-12-0)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 35 ℃; Cooling with ice;

DOI:10.1016/j.bmc.2013.07.049

Reference yield:

(E)-3,4-dimethoxybenzaldehyde oxime (39627-82-2) → N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride (105363-12-0)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 35 ℃; for 0.0166667h; Microwave irradiation; Sealed tube;

DOI:10.1016/j.bmc.2018.08.025

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → N-hydroxy-3,4-dimethoxybenzenecarboximidoyl chloride (105363-12-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / methanol; water / 12 h / 20 °C

2: N-chloro-succinimide / N,N-dimethyl-formamide / 5 h / 20 °C

With N-chloro-succinimide; hydroxylamine hydrochloride; sodium acetate; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2011.10.056

upstream raw materials:

3,4-Dimethoxy-benzaldehyde oxime

3,4-dimethoxy-benzaldehyde

(E)-3,4-dimethoxybenzaldehyde oxime

Downstream raw materials:

3-(3,4-Dimethoxy-phenyl)-6-hydroxy-5-undecyl-benzo[d]isoxazole-4,7-dione

3,4-dimethoxybenzonitrile oxide