1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline
CAS No.:65700-38-1
Molecular Formula:C₂₃H₃₁NO₄
Molecular Weight:385.503
Hs Code.:
NSC Number:127488
DSSTox Substance ID:DTXSID00299013
Nikkaji Number:J1.654.633J

Synonyms:65700-38-1;1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline;NSC127488;SCHEMBL11638212;DTXSID00299013;NSC-127488

Suppliers and Price of 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Vapor Pressure:7.71E-10mmHg at 25°C
Boiling Point:492.4°Cat760mmHg
Flash Point:134.5°C
Density:1.083g/cm³
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:385.22530847
Heavy Atom Count:28
Complexity:462

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC

Technology Process of 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline

There total 4 articles about 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-2-methyl-2-propyl-1,2,3,4-tetrahydro-isoquinolinium; chloride

: 65700-38-1
1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydro-isoquinoline

: (2-{2-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-4,5-dimethoxy-phenyl}-ethyl)-methyl-propyl-amine

Guidance literature:: With potassium thioacetate; In sulfolane; at 120 ℃; for 6h;
DOI:10.1039/b104843k

Reference yield:

: 1699-51-0,20412-65-1
laudanosine

: 65700-38-1
1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-2-propyl-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: K₃PO₄*3H₂O / tetrahydrothiophene 1,1-dioxide / 2 h / 110 °C

2: 212 mg / Na₂S*9H₂O / tetrahydrothiophene 1,1-dioxide / 5 h / 120 °C / Hoffmann elimination

With sodium sulfide; potassium phosphate; In sulfolane;
DOI:10.1039/b104843k