11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Base Information

Chemical Name:11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal
CAS No.:345653-88-5
Molecular Formula:C₂₉H₄₂O₃Si
Molecular Weight:466.736
Hs Code.:

Synonyms:11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Suppliers and Price of 11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

There total 13 articles about 11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 345653-87-4
Methyl 11(S)-(tert-butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenoate

: 345653-88-5
11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Guidance literature:: Methyl 11(S)-(tert-butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenoate; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 0.0833333h;

With dipyridinium dichromate; 4 A molecular sieve; In dichloromethane; at 20 ℃; for 1h; Further stages.;
DOI:10.1021/np000502q

Reference yield:

: 97974-23-7
(S)-2-(tert-butyldiphenylsilyloxy)-1-propanol

: 345653-88-5
11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Guidance literature:: Multi-step reaction with 11 steps

1.1: 64.42 g / pyridine / CH₂Cl₂ / 24.5 h / 0 - 20 °C

2.1: 93 percent / LiBr / tetrahydrofuran / 47 h / Heating

3.1: 76 percent / Li₂CuCl₄ / tetrahydrofuran; diethyl ether / 17 h / 20 °C

4.1: BH₃*THF / tetrahydrofuran / 1 h / 0 - 20 °C

4.2: 68 percent / Br₂; NaOMe / tetrahydrofuran; methanol / 5 - 20 °C

5.1: 75 percent / toluene / 48 h / Heating

6.1: PhLi / tetrahydrofuran; diethyl ether / 0.33 h / 20 °C

6.2: 54 percent / tetrahydrofuran; diethyl ether / 0.67 h / -40 - -30 °C

7.1: 80 percent / aq. AcOH / tetrahydrofuran / 47 h / Heating

8.1: 32 percent / Co(PPh₃)4 / tetrahydrofuran / 0.17 h / 0 °C

9.1: 69 percent / K₂CO₃ / 0.5 h / 0 °C

10.1: 99 percent / molecular sieves 4 Angstroem; proton sponge / CH₂Cl₂ / 3 h / 20 °C

11.1: DIBAL / CH₂Cl₂ / 0.08 h / -78 °C

11.2: 87 percent / molecular sieves 4 Angstroem; PDC / CH₂Cl₂ / 1 h / 20 °C

With pyridine; borane-THF; dilithium tetrachlorocuprate; Proton Sponge; tristriphenylphosphine cobalt chloride; 4 A molecular sieve; diisobutylaluminium hydride; potassium carbonate; acetic acid; phenyllithium; lithium bromide; In tetrahydrofuran; diethyl ether; dichloromethane; toluene; 6.2: Wittig-Schlosser reaction / 8.1: Reformatsky reaction;
DOI:10.1021/np000502q

Reference yield:

: 102732-44-5
ethyl (S)-2-(tert-butyldiphenylsilyloxy)propanoate

: 345653-88-5
11(S)-(tert-Butyldiphenylsilyloxy)-3R-methoxy-6E-dodecenal

Guidance literature:: Multi-step reaction with 12 steps

1.1: 100 percent / BH₃*THF / tetrahydrofuran / 2 h / Heating

2.1: 64.42 g / pyridine / CH₂Cl₂ / 24.5 h / 0 - 20 °C

3.1: 93 percent / LiBr / tetrahydrofuran / 47 h / Heating

4.1: 76 percent / Li₂CuCl₄ / tetrahydrofuran; diethyl ether / 17 h / 20 °C

5.1: BH₃*THF / tetrahydrofuran / 1 h / 0 - 20 °C

5.2: 68 percent / Br₂; NaOMe / tetrahydrofuran; methanol / 5 - 20 °C

6.1: 75 percent / toluene / 48 h / Heating

7.1: PhLi / tetrahydrofuran; diethyl ether / 0.33 h / 20 °C

7.2: 54 percent / tetrahydrofuran; diethyl ether / 0.67 h / -40 - -30 °C

8.1: 80 percent / aq. AcOH / tetrahydrofuran / 47 h / Heating

9.1: 32 percent / Co(PPh₃)4 / tetrahydrofuran / 0.17 h / 0 °C

10.1: 69 percent / K₂CO₃ / 0.5 h / 0 °C

11.1: 99 percent / molecular sieves 4 Angstroem; proton sponge / CH₂Cl₂ / 3 h / 20 °C

12.1: DIBAL / CH₂Cl₂ / 0.08 h / -78 °C

12.2: 87 percent / molecular sieves 4 Angstroem; PDC / CH₂Cl₂ / 1 h / 20 °C

With pyridine; borane-THF; dilithium tetrachlorocuprate; Proton Sponge; tristriphenylphosphine cobalt chloride; 4 A molecular sieve; diisobutylaluminium hydride; potassium carbonate; acetic acid; phenyllithium; lithium bromide; In tetrahydrofuran; diethyl ether; dichloromethane; toluene; 7.2: Wittig-Schlosser reaction / 9.1: Reformatsky reaction;
DOI:10.1021/np000502q