Rifamycin O

Base Information

Chemical Name:Rifamycin O
CAS No.:14487-05-9
Molecular Formula:C39H47NO14
Molecular Weight:753.8
Hs Code.:
European Community (EC) Number:238-493-1
DSSTox Substance ID:DTXSID201023447
Metabolomics Workbench ID:21318
Wikidata:Q27101853
Mol file:14487-05-9.mol

Synonyms:rifamycin O

Suppliers and Price of Rifamycin O

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Adipogen Life Sciences
RifamycinO ≥90%(HPLC)
50 mg
$ 70.00

Adipogen Life Sciences
RifamycinO ≥90%(HPLC)
500 mg
$ 380.00

AHH
RifamycinO 98%
0.1g
$ 610.00

AK Scientific
RifamycinO
250mg
$ 421.00

Ambeed
Spiro[1,3-dioxolane-2,9'(6'H)-[2,7](epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan]-1',4,6',11'(2'H)-tetrone,5',17',19',21'-tetrahydroxy-23'-methoxy-2',4',12',16',18',20',22'-heptamethyl-21'-acetate 97%
5g
$ 19.00

Ambeed
Spiro[1,3-dioxolane-2,9'(6'H)-[2,7](epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan]-1',4,6',11'(2'H)-tetrone,5',17',19',21'-tetrahydroxy-23'-methoxy-2',4',12',16',18',20',22'-heptamethyl-21'-acetate 97%
25g
$ 72.00

Ambeed
Spiro[1,3-dioxolane-2,9'(6'H)-[2,7](epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan]-1',4,6',11'(2'H)-tetrone,5',17',19',21'-tetrahydroxy-23'-methoxy-2',4',12',16',18',20',22'-heptamethyl-21'-acetate 97%
100g
$ 228.00

American Custom Chemicals Corporation
RIFAMYCIN O 95.00%
1MG
$ 152.25

American Custom Chemicals Corporation
RIFAMYCIN O 95.00%
100MG
$ 704.55

American Custom Chemicals Corporation
RIFAMYCIN O 95.00%
1G
$ 1593.90

Total 105 raw suppliers

Chemical Property of Rifamycin O

Chemical Property:

Appearance/Colour:Yellow solid
Melting Point:171°C (dec.)
Refractive Index:1.607
Boiling Point:972.841 °C at 760 mmHg
PKA:4.61±0.70(Predicted)
Flash Point:542.155 °C
PSA：213.45000
Density:1.366 g/cm³
LogP:3.50260
Storage Temp.:-20?C Freezer, Under Inert Atmosphere
XLogP3:4.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:3
Exact Mass:753.29965517
Heavy Atom Count:54
Complexity:1640

Purity/Quality:

99% ^*data from raw suppliers

RifamycinO ≥90%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C=CC=C(C(=O)NC2=CC3(C4=C(C2=O)C(=C(C5=C4C(=O)C(O5)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O3)C
Isomeric SMILES:C[C@H]1/C=C/C=C(\C(=O)NC2=CC3(C4=C(C2=O)C(=C(C5=C4C(=O)[C@](O5)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O3)/C
Uses Rifamycin O (Rifaximin EP Impurity F) is a Rifaximin intermediate.

Technology Process of Rifamycin O

There total 3 articles about Rifamycin O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 13929-35-6
rifamycin B

: 14487-05-9
rifamycin O

Guidance literature:: With manganese(IV) oxide; In benzene; for 0.0833333h; Ambient temperature;
DOI:10.1246/cl.1982.627

Reference yield: 80.0%

: 13929-35-6
Rifamycin B

: 14487-05-9
rifamycin O

Guidance literature:: With air; Ambient temperature;
DOI:10.1021/jm970791o

Reference yield:

: 13929-35-6
Rifamycin B

: 62623-68-1,76188-88-0,81203-58-9,101978-28-3,13553-79-2
rifamycin S

: 14487-05-9
rifamycin O

Guidance literature:: With ammonium persulfate; In methanol; aq. phosphate buffer; at 60 ℃; for 4h; Solvent; Reagent/catalyst;
DOI:10.1021/acs.oprd.5b00070