[2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene

Base Information

• Chemical Name: [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene
• CAS No.: 1370658-65-3
• Molecular Formula: C₂₉H₂₇FeN₃O₃
• Molecular Weight: 521.399
• Mol file: 1370658-65-3.mol

Synonyms:[2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene

Chemical Property of [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene

There total 2 articles about [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,2-dimethyl-5-ferrocenylmethylene-1,3-dioxane-4,6-dione (98345-59-6) + 2,6-dimethylphenyl isonitrile (119072-54-7,2769-71-3) + 1,2-diamino-benzene (95-54-5) → [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene (1370658-65-3)

Guidance literature:

With water; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1002/jhet.1041

Reference yield: 58.0%

cycl-isopropylidene malonate (2033-24-1) + ferrocenecarboxaldehyde (12093-10-6) + 2,6-dimethylphenyl isonitrile (119072-54-7,2769-71-3) + water (7732-18-5) + 1,2-diamino-benzene (95-54-5) → [2-((2,6-dimethylphenyl)amino)-2-oxo-1-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)ethyl]ferrocene (1370658-65-3)

Guidance literature:

In dichloromethane; stirring mixt. of diaminobenzene, Meldrum's acid, ferrocenecarboxaldehyde, isocyanide deriv. and water in CH2Cl2 for 36 h at room temp.; addn. of hexane, filtration, washing with ethanol, elem. anal.;

DOI:10.1002/hlca.201100313

upstream raw materials:

cycl-isopropylidene malonate

ferrocenecarboxaldehyde

2,6-dimethylphenyl isonitrile

water