11-Hydroxyaporphine hydrobromide

Base Information

• Chemical Name: 11-Hydroxyaporphine hydrobromide
• CAS No.: 53055-01-9
• Molecular Formula: BrH*C₁₇H₁₇NO
• Molecular Weight: 332.24
• DSSTox Substance ID: DTXSID30967551
• Mol file: 53055-01-9.mol

Synonyms:11-hydroxyaporphine

Chemical Property of 11-Hydroxyaporphine hydrobromide

Chemical Property:

• Vapor Pressure: 3.99E-08mmHg at 25°C
• Boiling Point: 433.6°Cat760mmHg
• Flash Point: 236.2°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 331.05718
• Heavy Atom Count: 20
• Complexity: 344

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=CC=C4)O.Br

Technology Process of 11-Hydroxyaporphine hydrobromide

There total 11 articles about 11-Hydroxyaporphine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(R)-(-)-11-methoxyaporphine hydrochloride (83207-97-0) → (R)-(-)-11-hydroxyaporphine hydrobromide (83247-89-6,53055-01-9)

Guidance literature:

With hydrogen bromide; at 115 - 120 ℃; for 4h;

DOI:10.1021/jo00143a050

Reference yield: 72.0%

(R)-(-)-11-methoxyaporphine (121617-59-2) → (R)-(-)-11-hydroxyaporphine hydrobromide (83247-89-6,53055-01-9)

Guidance literature:

With hydrogen bromide; for 4h; Heating;

DOI:10.1021/jm00164a022

Reference yield: 66.0%

(R)-11-tert-Butoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline (213390-15-9) → (R)-(-)-11-hydroxyaporphine hydrobromide (83247-89-6,53055-01-9)

Guidance literature:

With hydrogen bromide; at 130 ℃; for 0.416667h;

DOI:10.1002/jhet.5570350307

upstream raw materials:

(S)-(+)-11-methoxyaporphine

(R)-(-)-11-methoxyaporphine

(R)-(-)-11-methoxyaporphine hydrochloride

(R)-11-tert-Butoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline