(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

Base Information

Chemical Name:(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester
CAS No.:19707-45-0
Molecular Formula:C₁₇H₂₂N₂O₅
Molecular Weight:334.372
Hs Code.:

(<i>R</i>)-α-[(<i>S</i>)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

Synonyms:(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

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Chemical Property of (R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

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Technology Process of (R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

There total 5 articles about (R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2315-05-1
methyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

: 19707-45-0
(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

Guidance literature:: With 2,2'-azobis(isobutyronitrile); triphenylstannane; In benzene; for 2h; Heating;

Reference yield: 14.0%

: 124870-92-4
(R)-2-[(2R,3R)-2-Mercapto-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-3-methyl-butyric acid methyl ester

: 19707-45-0
(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

: 124870-93-5
(R)-3-Methyl-2-[(2-phenoxymethyl-thiazole-4-carbonyl)-amino]-butyric acid methyl ester

Guidance literature:: With 2,2'-azobis(isobutyronitrile); triphenylstannane; In benzene; for 4h; Heating;

Reference yield:

: (R)-3-Methyl-2-((1R,5R)-7-oxo-3-phenoxymethyl-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-butyric acid methyl ester

: 19707-45-0
(R)-α-[(S)-2-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-isovaleric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2N HCl / acetone / 1.5 h / 0 °C

2: 50 percent / triphenylstannane, AIBN / benzene / 4 h / Heating

With hydrogenchloride; 2,2'-azobis(isobutyronitrile); triphenylstannane; In acetone; benzene;