4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester

Base Information

• Chemical Name: 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester
• CAS No.: 1026003-26-8
• Molecular Formula: C₁₉H₁₈N₂O₃S
• Molecular Weight: 354.43
• Mol file: 1026003-26-8.mol

Synonyms:4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester

Chemical Property of 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester

There total 1 articles about 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-N-<<(4-methoxycarbonyl)phenyl>methyl>-1-methyl-1H-indole-3-carboxamide (156136-86-6) → 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester (1026003-26-8)

Guidance literature:

With lithium methanethiolate; In N,N-dimethyl acetamide; at 80 ℃; for 6h;

DOI:10.1021/jm00001a011

Reference yield:

4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester (1026003-26-8) → 4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 90h;

DOI:10.1021/jm00001a011

Reference yield:

4-{[(1-Methyl-2-thioxo-2,3-dihydro-1H-indole-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester (1026003-26-8) → 2,2'-dithiobis [N-(4'-carbomethoxy)benzyl 1-methylindolyl-3-carboxamide]

Guidance literature:

With dihydrogen peroxide; In methanol; Yield given;

DOI:10.1021/jm00001a011

upstream raw materials:

2-chloro-N-<<(4-methoxycarbonyl)phenyl>methyl>-1-methyl-1H-indole-3-carboxamide