tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Base Information

Chemical Name:tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate
CAS No.:870133-58-7
Molecular Formula:C₅₉H₇₄F₃NO₁₂
Molecular Weight:1046.23
Hs Code.:

Synonyms:tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Suppliers and Price of tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

There total 2 articles about tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2S,4R,5S)-2-(4-Methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester

: 870133-58-7
tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / toluene / 16 h / 80 °C

2: 79 percent / 4-(dimethylamino)pyridine / pyridine / 3 h / 90 °C

With dmap; dicyclohexyl-carbodiimide; In pyridine; toluene;
DOI:10.1002/ejoc.200500203

Reference yield:

: 130781-88-3
tert-butyl 3α,7α-dihydroxy-12α-trifluoroacetoxy-5β-cholan-24-oate

: 870133-58-7
tert-butyl 7α-benzoyloxy-3-α-[N-Boc-N,O-(4-methoxybenzylidene)-β-phenylisoserinoyl]-12α-trifluoroacetoxy-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / toluene / 16 h / 80 °C

2: 79 percent / 4-(dimethylamino)pyridine / pyridine / 3 h / 90 °C

With dmap; dicyclohexyl-carbodiimide; In pyridine; toluene;
DOI:10.1002/ejoc.200500203