Technology Process of C27H24N6O4
There total 6 articles about C27H24N6O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-tetrahydropyran-1H-pyrazolylboronic ester; 6-bromo-N-(2-morpholino-5-(piperidin-1-yl)benzo[d]oxazol-6-yl)picolinamide;
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate;
In
1,4-dioxane; water;
at 100 - 120 ℃;
for 3h;
Sealed tube;
Inert atmosphere;
With
hydrogenchloride;
In
diethyl ether;
at 0 - 30 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: iron; hydrogenchloride / ethanol; water / 1 h / 70 - 80 °C
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 - 30 °C
3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 3 h / 100 - 120 °C / Sealed tube; Inert atmosphere
3.2: 0 - 30 °C
With
hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; iron; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
1,4-dioxane; ethanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 - 30 °C
2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 3 h / 100 - 120 °C / Sealed tube; Inert atmosphere
2.2: 0 - 30 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
1,4-dioxane; water; N,N-dimethyl-formamide;