(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Base Information

Chemical Name:(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate
CAS No.:1299293-79-0
Molecular Formula:C₃₆H₅₆O₆Si
Molecular Weight:612.923
Hs Code.:

Synonyms:(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Suppliers and Price of (1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

There total 14 articles about (1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1299293-74-5
ethyl (4S,5R)-5-{[tert-butyl(dimethyl)silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

: 1299293-79-0
(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; sodium hydroxide / ethanol / 0 - 20 °C

2.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / toluene / 0.5 h / 20 °C

2.2: 2 h

With 2,4,6-trichlorobenzoyl chloride; water; triethylamine; sodium hydroxide; In ethanol; toluene;
DOI:10.1055/s-0030-1259287

Reference yield:

: 1299293-72-3
(4R)-4-benzyl-3-{(2R,3R)-3-{[tert-butyl(dimethyl)silyl]oxy}-4-[(4-methoxybenzyl)oxy]-2-methylbutanoyl}-1,3-oxazolidin-2-one

: 1299293-79-0
(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: lithium borohydride / tetrahydrofuran; methanol / 19 h / 0 - 20 °C

2.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C

3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride / acetonitrile / 1 h / 0 °C

3.2: 0 - 20 °C

4.1: 10% palladium on activated charcoal; hydrogen / ethyl acetate / 18 h / 20 °C

5.1: water; sodium hydroxide / ethanol / 0 - 20 °C

6.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / toluene / 0.5 h / 20 °C

6.2: 2 h

With lithium borohydride; 2,4,6-trichlorobenzoyl chloride; 10% palladium on activated charcoal; water; hydrogen; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; lithium chloride; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; toluene; acetonitrile; 2.1: Dess-Martin oxidation / 3.1: Wittig-Horner reaction / 3.2: Wittig-Horner reaction;
DOI:10.1055/s-0030-1259287

Reference yield:

: 109786-74-5,109786-77-8,13807-95-9
(±)-3-(4-methoxybenzyloxy)propane-1,2-diol

: 1299293-79-0
(1R,2S)-1-[2-(benzyloxy)ethyl]-2-methylpent-4-en-1-yl (4S,5R)-5-{[tert-butyl(dimethyl)-silyl]oxy}-6-[(4-methoxybenzyl)oxy]-4-methylhexanoate

Guidance literature:: Multi-step reaction with 9 steps

1.1: sodium periodate; water / dichloromethane / 0 - 20 °C

2.1: di-n-butylboryl trifluoromethanesulfonate; triethylamine / dichloromethane / 0 °C

2.2: 1.33 h / -80 - 0 °C

3.1: 2,6-dimethylpyridine / dichloromethane / 0 - 20 °C

4.1: lithium borohydride / tetrahydrofuran; methanol / 19 h / 0 - 20 °C

5.1: Dess-Martin periodane / dichloromethane / 3 h / 0 - 20 °C

6.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride / acetonitrile / 1 h / 0 °C

6.2: 0 - 20 °C

7.1: 10% palladium on activated charcoal; hydrogen / ethyl acetate / 18 h / 20 °C

8.1: water; sodium hydroxide / ethanol / 0 - 20 °C

9.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / toluene / 0.5 h / 20 °C

9.2: 2 h

With 2,6-dimethylpyridine; sodium periodate; lithium borohydride; di-n-butylboryl trifluoromethanesulfonate; 2,4,6-trichlorobenzoyl chloride; 10% palladium on activated charcoal; water; hydrogen; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; lithium chloride; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; toluene; acetonitrile; 5.1: Dess-Martin oxidation / 6.1: Wittig-Horner reaction / 6.2: Wittig-Horner reaction;
DOI:10.1055/s-0030-1259287