N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester

Base Information

Chemical Name:N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester
CAS No.:1187430-26-7
Molecular Formula:C₁₉H₂₄F₂N₂O₅
Molecular Weight:398.407
Hs Code.:

Synonyms:N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester

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Technology Process of N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester

There total 1 articles about N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1738-76-7
glycine benzyl ester p-toluenesulfonic acid salt

: 203866-15-3
1-(tert-butoxycarbonyl)-4,4-difluoro-L-proline

: 1187430-26-7
N-tert-butoxycarbonyl-(2S)-4,4-difluoroprolylglycine benzyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2009.03.168