4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

Base Information

Chemical Name:4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one
CAS No.:771-26-6
Molecular Formula:C8H7NO3
Molecular Weight:165.148
Hs Code.:2934999090
Mol file:771-26-6.mol

Synonyms:3,4-dihydro-4-hydroxy-3-oxo-2H-1,4-benzoxazine;4-hydroxy-2H-1,4-benzoxazin-3-one;4-hydroxy-1,4-benzoxazine-3-one;

Suppliers and Price of 4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Deoxy-DIBOA
5g
$ 1735.00

Apolloscientific
4-Hydroxy-3,4-dihydro-2H-1,4-benzoxazin-3-one tech
1g
$ 1378.00

American Custom Chemicals Corporation
4-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 95.00%
5MG
$ 697.51

American Custom Chemicals Corporation
4-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 95.00%
10MG
$ 692.49

American Custom Chemicals Corporation
4-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 95.00%
1MG
$ 658.53

AK Scientific
4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one
1g
$ 1043.00

AK Scientific
4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one
500mg
$ 835.00

Total 6 raw suppliers

Chemical Property of 4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

Chemical Property:

Vapor Pressure:7.2E-05mmHg at 25°C
Melting Point:168-169 °C(Solv: water (7732-18-5))
Boiling Point:329.3°C at 760 mmHg
PKA:8.04±0.20(Predicted)
Flash Point:153°C
PSA：49.77000
Density:1.476g/cm³
LogP:0.86620

Purity/Quality:

97% ^*data from raw suppliers

2-Deoxy-DIBOA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Deoxy-DIBOA is a derivative of DIBOA (D422730), an allelopathic biochemical that is produced by grasses. This benzoxazinoid compound displays health-promoting effects in rats.

Technology Process of 4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one

There total 11 articles about 4-Hydroxy-2H-1,4-benzoxazin-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 37682-31-8
ethyl o-nitrophenoxyacetate

: 771-26-6
4-hydroxy-2H-1,4-benzoxazin-3-one

Guidance literature:: With ammonium chloride; zinc; In ethanol; at 30 - 40 ℃; for 2h;
DOI:10.1055/s-1989-27203

Reference yield: 85.0%

: 153720-70-8
4-Allyloxy-4H-benzo[1,4]oxazin-3-one

: 771-26-6
4-hydroxy-2H-1,4-benzoxazin-3-one

Guidance literature:: With palladium diacetate; triethylammonium formate; triphenylphosphine; In ethanol; water; for 0.166667h; Heating;
DOI:10.3987/COM-93-S1

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 771-26-6
4-hydroxy-2H-1,4-benzoxazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: KOH / ethanol / 1 h

1.2: 99 percent / dimethylformamide / 24 h

2.1: 70 percent / NaBH₄ / Pd/C / H₂O; dioxane

With potassium hydroxide; sodium tetrahydroborate; palladium on activated charcoal; In 1,4-dioxane; ethanol; water;
DOI:10.1021/jf062709g