2-acetamido-2,6-dideoxy-6-fluorogalactose

Base Information

• Chemical Name: 2-acetamido-2,6-dideoxy-6-fluorogalactose
• CAS No.: 112289-45-9
• Molecular Formula: C₈H₁₄FNO₅
• Molecular Weight: 223.201
• Mol file: 112289-45-9.mol

Synonyms:2-acetamido-2,6-dideoxy-6-fluorogalactose

Chemical Property of 2-acetamido-2,6-dideoxy-6-fluorogalactose

Chemical Property:

• Vapor Pressure: 5.76E-16mmHg at 25°C
• Boiling Point: 581.9°Cat760mmHg
• PKA: 13.00±0.20(Predicted)
• Flash Point: 305.7°C
• PSA: 0.00000
• Density: 1.366g/cm³
• LogP: 0.00000

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetamido-2,6-dideoxy-6-fluorogalactose

There total 2 articles about 2-acetamido-2,6-dideoxy-6-fluorogalactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-deoxy-9-deoxy-9-fluoro-NeuAc → N-((1S,2R,3S,4S)-5-Fluoro-1-formyl-2,3,4-trihydroxy-pentyl)-acetamide (86230-29-7,112289-45-9)

Guidance literature:

With 1,4-dihydronicotinamide adenine dinucleotide; aldolase;

DOI:10.1021/ja982950e

Reference yield:

3-deoxy-9-deoxy-9-fluoro-NeuAc → 2-oxo-propionic acid (127-17-3) + N-((1S,2R,3S,4S)-5-Fluoro-1-formyl-2,3,4-trihydroxy-pentyl)-acetamide (86230-29-7,112289-45-9)

Guidance literature:

With L-lactate dehydrogenase; NauAc aldolase; NADH; In water; at 37 ℃; pH=7.0; Further Variations:; var. conc.; Enzyme kinetics; Enzymatic reaction;

DOI:10.1021/ja994211j

Refernces

• 1、 Miyazaki, Tatsuo,Sato, Hajime,Sakakibara, Tohru,Kajihara, Yasuhiro. "An approach to the precise chemoenzymatic synthesis of 13C-labeled sialyloligosaccharide on an intact glycoprotein: A novel one-pot [3-13C]-labeling method for sialic acid analogues by control of the reversible aldolase reaction, enzymatic synthesis of [3-13C]-NeuAc-α-(2→3)-[U- 13C]-Gal-β-(1-4)-GlcNAc-β-sequence onto glycoprotein". . p. 5678 - 5694. Retrieved 2007/10/03.