ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

Base Information

Chemical Name:ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate
CAS No.:1211383-10-6
Molecular Formula:C₁₉H₂₉F₂NO₃S
Molecular Weight:389.507
Hs Code.:

Synonyms:ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

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Technology Process of ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

There total 8 articles about ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 957121-16-3
methyl 5-(3,5-difluorophenyl)-2,2-dimethyl-5-oxopentanoate

: 343338-28-3
(S)-2-methylpropane-2-sulfinamide

: 957121-18-5
methyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

: 1211383-10-6
ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

Guidance literature:: methyl 5-(3,5-difluorophenyl)-2,2-dimethyl-5-oxopentanoate; (S)-2-methylpropane-2-sulfinamide; titanium(IV) tetraethanolate; In tetrahydrofuran; at 60 ℃; for 3h; Inert atmosphere;

With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

Reference yield:

: titanium(IV) tetraethanolate

: 957121-16-3
methyl 5-(3,5-difluorophenyl)-2,2-dimethyl-5-oxopentanoate

: 343338-28-3
(S)-2-methylpropane-2-sulfinamide

: 957121-18-5
methyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

: 1211383-10-6
ethyl (5S)-5-{[(S)-tert-butylsulfinyl]amino}-5-(3,5-difluorophenyl)-2,2-dimethylpentanoate

Guidance literature:: titanium(IV) tetraethanolate; methyl 5-(3,5-difluorophenyl)-2,2-dimethyl-5-oxopentanoate; (S)-2-methylpropane-2-sulfinamide; In tetrahydrofuran; at 60 ℃; for 3h; Sealed vessel;

With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 0.25h;