C₁₂H₁₂BrFO₂

Base Information

Chemical Name:C₁₂H₁₂BrFO₂
CAS No.:1359856-95-3
Molecular Formula:C₁₂H₁₂BrFO₂
Molecular Weight:287.128
Hs Code.:

C<sub>12</sub>H<sub>12</sub>BrFO<sub>2</sub>

Synonyms:C₁₂H₁₂BrFO₂

Suppliers and Price of C₁₂H₁₂BrFO₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of C₁₂H₁₂BrFO₂

Chemical Property:

Purity/Quality:: 95-3484%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of C₁₂H₁₂BrFO₂

There total 2 articles about C₁₂H₁₂BrFO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1255794-73-0
2-bromo-3-(hydroxymethyl)benzaldehyde

: 1359856-95-3
C₁₂H₁₂BrFO₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 50 °C

2.1: potassium tert-butylate / dimethyl sulfoxide / 1 h / 0 °C

2.2: 3 h / 0 - 20 °C

With potassium tert-butylate; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; 2.1: Wittig reaction / 2.2: Wittig reaction;
DOI:10.1016/j.bmcl.2011.12.096

Reference yield:

: 1269411-36-0
methyl 2-bromo-3-(1,3-dioxolan-2-yl)benzoate

: 1359856-95-3
C₁₂H₁₂BrFO₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tetrahydroborate / ethanol / 48 h / 0 - 20 °C

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 50 °C

3.1: potassium tert-butylate / dimethyl sulfoxide / 1 h / 0 °C

3.2: 3 h / 0 - 20 °C

With sodium tetrahydroborate; potassium tert-butylate; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; dimethyl sulfoxide; 3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1016/j.bmcl.2011.12.096

Reference yield: 38.0%

: 1359856-95-3
C₁₂H₁₂BrFO₂

: 1359856-96-4
C₁₂H₁₁Br₂FO₂

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; at 85 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.bmcl.2011.12.096