1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

Base Information

Chemical Name:1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide
CAS No.:1354824-90-0
Molecular Formula:BrH*C₁₆H₂₀N₆
Molecular Weight:377.287
Hs Code.:

Synonyms:1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

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Chemical Property of 1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

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Technology Process of 1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

There total 4 articles about 1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1354825-88-9
[2-(4-amino-3-(4-methylphenyl)-pyrazolo[3,4-d]pyrimidin-1-yl)-2-methyl-propyl]-carbamic acid benzyl ester

: 1354824-90-0
1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

Guidance literature:: With hydrogen bromide; acetic acid; at 20 ℃; for 1h;

Reference yield:

: 1354825-87-8
[2-(5-amino-4-cyano-3-(4-methylphenyl)-pyrazol-1-yl)-2-methyl-propyl]-carbamic acid benzyl ester

: 1354824-90-0
1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: 2-methoxy-ethanol / 1 h / 150 °C

2: hydrogen bromide; acetic acid / 1 h / 20 °C

With hydrogen bromide; acetic acid; In 2-methoxy-ethanol;

Reference yield:

: (x)C₇H₈O₃S*C₁₂H₁₉N₃O₂

: 1354824-90-0
1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / ethanol / 3 h / 60 °C

2: 2-methoxy-ethanol / 1 h / 150 °C

3: hydrogen bromide; acetic acid / 1 h / 20 °C

With hydrogen bromide; acetic acid; triethylamine; In ethanol; 2-methoxy-ethanol;