Carbonic acid tert-butyl ester 3-formyl-4-nitro-phenyl ester

Base Information

• Chemical Name: Carbonic acid tert-butyl ester 3-formyl-4-nitro-phenyl ester
• CAS No.: 1027818-09-2
• Molecular Formula: C₁₂H₁₃NO₆
• Molecular Weight: 267.238
• Mol file: 1027818-09-2.mol

Synonyms:C₁₂H₁₃NO₆

Chemical Property of Carbonic acid tert-butyl ester 3-formyl-4-nitro-phenyl ester

Chemical Property:

• Boiling Point: 409.3±45.0 °C(Predicted)
• Density: 1.294±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C

Purity/Quality:

tert-Butyl(3-formyl-4-nitrophenyl)carbonate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonic acid tert-butyl ester 3-formyl-4-nitro-phenyl ester

There total 1 articles about Carbonic acid tert-butyl ester 3-formyl-4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-nitro-5-hydroxybenzaldehyde (42454-06-8) + di-tert-butyl dicarbonate (24424-99-5) → C12H13NO6 (1027818-09-2)

Guidance literature:

With dmap; In acetonitrile; at 20 ℃;

DOI:10.1002/jlcr.1240

Reference yield: 51.0%

C12H13NO6 (1027818-09-2) → C12H15NO4 (161914-18-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethyl acetate; at 20 ℃;

DOI:10.1002/jlcr.1240

Reference yield:

C12H13NO6 (1027818-09-2) → C13H19NO7(13)C4 (1027818-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 51 percent / H₂ / PtO₂ / ethyl acetate / 20 °C

2: 66 percent / PhNMe₂ / CH₂Cl₂ / 20 °C

With hydrogen; N,N-dimethyl-aniline; platinum(IV) oxide; In dichloromethane; ethyl acetate;

DOI:10.1002/jlcr.1240

upstream raw materials:

2-nitro-5-hydroxybenzaldehyde

di-tert-butyl dicarbonate

Downstream raw materials:

C₁₂H₁₅NO₄

C₁₃H₁₉NO₇⁽¹³⁾C₄

C₄₅H₆₅O₁₁N⁽¹³⁾C₄

Refernces