N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide

Base Information

• Chemical Name: N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide
• CAS No.: 2848-94-4
• Molecular Formula: C16H13 Br Cl N O2
• Molecular Weight: 366.642
• Hs Code.: 2924299090
• European Community (EC) Number: 220-652-1
• DSSTox Substance ID: DTXSID60182710
• Nikkaji Number: J306.776I
• Wikidata: Q83053419
• Mol file: 2848-94-4.mol

Synonyms:N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide;2848-94-4;EINECS 220-652-1;SCHEMBL10805397;C16-H13-Br-Cl-N-O2;DTXSID60182710;2-(N-methyl-bromoacetamido)-5-chlorobenzophenone;2-(2-bromo-N-methylacetamido)-5-chlorobenzophenone

Chemical Property of N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide

Chemical Property:

• Vapor Pressure: 6.51E-11mmHg at 25°C
• Boiling Point: 520°C at 760 mmHg
• Flash Point: 268.3°C
• PSA: 37.38000
• Density: 1.5g/cm³
• LogP: 3.92870
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 364.98182
• Heavy Atom Count: 21
• Complexity: 385

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2)C(=O)CBr

Technology Process of N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide

There total 2 articles about N-(2-Benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromoacetyl chloride (22118-09-8) + 5-chloro-2-(methylamino)benzophenone (1022-13-5) → N-(2-benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide (2848-94-4)

Guidance literature:

In toluene; Solvent;

DOI:10.1002/ejoc.201601270

Reference yield:

→ N-(2-benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide (2848-94-4)

Guidance literature:

2-Methylamino-5-chlor-benzophenon u. Bromacetylbromid i. Ae./Eis;

Reference yield:

N-(2-benzoyl-4-chlorophenyl)-2-bromo-N-methylacetamide (2848-94-4) → diazepam (439-14-5)

Guidance literature:

With ammonium bromide; hexamethylenetetramine; In aqueous isopropyl alcohol;

upstream raw materials:

2-bromoacetyl chloride

5-chloro-2-(methylamino)benzophenone

Downstream raw materials:

6-chloro-3,4-epoxy-1-methyl-4-phenyl-3,4-dihydro-1H-quinolin-2-one

diazepam