(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Base Information

Chemical Name:(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide
CAS No.:1351067-19-0
Molecular Formula:C₂₉H₃₄N₂OSi
Molecular Weight:454.687
Hs Code.:

Synonyms:(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Suppliers and Price of (Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

There total 5 articles about (Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 3-phenyl-N-(quinolin-8-yl)acrylamide

: 89343-06-6
tris-iso-propylsilyl acetylene

: 1351067-19-0
(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Guidance literature:: With cobalt(III) acetylacetonate; manganese(II) acetate; silver carbonate; In tetrahydrofuran; at 120 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c9cc02347j

Reference yield: 66.0%

: 905774-57-4
3-phenyl-N-(quinolin-8-yl)acrylamide

: 111409-79-1
1-bromo-2-(triisopropylsilyl)acetylene

: 1351067-19-0
(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Guidance literature:: With cesium acetate; palladium diacetate; In toluene; at 110 ℃; for 15h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol203100u

Reference yield:

: 102-92-1,17082-09-6
cinnamoyl chloride

: 1351067-19-0
(Z)-3-phenyl-N-(quinolin-8-yl)-5-(triisopropylsilyl)pent-2-en-4-ynamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

2: cesium acetate; palladium diacetate / toluene / 15 h / 110 °C / Inert atmosphere

With cesium acetate; palladium diacetate; triethylamine; In dichloromethane; toluene;
DOI:10.1021/ol203100u