3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one

Base Information

Chemical Name:3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one
CAS No.:100071-89-4
Molecular Formula:C₂₃H₃₂O₅
Molecular Weight:388.504
Hs Code.:
European Community (EC) Number:600-023-1
DSSTox Substance ID:DTXSID901144042
Nikkaji Number:J675.354J

Synonyms:DTXSID901144042;3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one;Gon-5-ene-3,11,17-trione, 13-ethyl-, cyclic 3,17-bis(1,2-ethanediyl acetal);100071-89-4

Suppliers and Price of 3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:388.22497412
Heavy Atom Count:28
Complexity:702

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC12CC(=O)C3C4CCC5(CC4=CCC3C1CCC26OCCO6)OCCO5
Isomeric SMILES:CC[C@]12CC(=O)[C@@H]3[C@H]4CCC5(CC4=CC[C@H]3[C@@H]1CCC26OCCO6)OCCO5

Technology Process of 3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one

There total 1 articles about 3,3:17,17-Bis(ethylenedioxy)-13beta-ethylgon-5-en-11-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53067-82-6,170901-07-2
13β-ethyl-11α-hydroxygon-5-ene-3,17-dione

: 100071-89-4
18a-homoestr-5-ene-3,11,17-trione cyclic 3,17-bis(1,2-ethanediyl acetal)

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / HC(OEt)3, PTS / benzene / 6 h / Heating

2: 87 percent / PDC / CH₂Cl₂ / 8 h / Ambient temperature

With dipyridinium dichromate; pyridinium p-toluenesulfonate; orthoformic acid triethyl ester; In dichloromethane; benzene;
DOI:10.1080/00397919708006801

Reference yield:

: 100071-89-4
18a-homoestr-5-ene-3,11,17-trione cyclic 3,17-bis(1,2-ethanediyl acetal)

: 54024-22-5
desogestrel

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / 57 percent NaH / dimethylsulfoxide; paraffin / 1.) 75 deg C; 2.) 60 deg C, 3 h

2: 83 percent / conc. HCl / acetone / 4.5 h / Ambient temperature

3: 91 percent / BF₃*Et₂O / tetrahydrofuran / 2.75 h / Heating

4: t-BuOK / tetrahydrofuran / 2 h / -20 - -15 °C

5: 58 percent / Na / liquid ammonia; tetrahydrofuran / 1 h / -4 °C

With hydrogenchloride; boron trifluoride diethyl etherate; potassium tert-butylate; sodium; sodium hydride; In tetrahydrofuran; ammonia; dimethyl sulfoxide; acetone; paraffin;
DOI:10.1002/recl.19881070406

Reference yield:

: 100071-89-4
18a-homoestr-5-ene-3,11,17-trione cyclic 3,17-bis(1,2-ethanediyl acetal)

: 11β-(4-methoxyphenyl)-18a-homoestr-5-ene-3,17-dione cyclic bis(1,2-ethanediyl acetal)

Guidance literature:: Multi-step reaction with 3 steps

1: 28 percent / 2,6-di-tert-butylpyridine / CH₂Cl₂ / 24 h / Ambient temperature

2: 27 percent / LiCl, 2 M aq. Na₂CO₃ / Pd(PPh₃)4 / ethanol; toluene / 1 h / Heating

3: 82 percent / Li, liq. NH₃ / tetrahydrofuran / 1 h / -78 °C

With 2,6-di-tert-butyl-pyridine; ammonia; lithium; sodium carbonate; lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; dichloromethane; toluene;
DOI:10.1002/prac.19973390164