2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine

Base Information

• Chemical Name: 2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine
• CAS No.: 1616667-77-6
• Molecular Formula: C₂₀H₁₉F₃N₄O₅
• Molecular Weight: 452.39
• Mol file: 1616667-77-6.mol

Synonyms:2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine

Chemical Property of 2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine

There total 1 articles about 2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

m-trifluoromethylphenyl iodide (401-81-0) + 2',3'-O-isopropylideneinosine (2140-11-6) → 2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine (1616667-77-6)

Guidance literature:

With piperidine; copper(l) iodide; palladium diacetate; caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 1h; Microwave irradiation;

DOI:10.1016/j.ejmech.2014.05.073

Reference yield: 60.0%

2',3'-O-isopropylidene-8-(3-trifluoromethylphenyl)inosine (1616667-77-6) → 8-(3-trifluoromethylphenyl)inosine (1616667-80-1)

Guidance literature:

With trifluoroacetic acid; In 1,4-dioxane; water; at 20 ℃; for 0.25h;

DOI:10.1016/j.ejmech.2014.05.073

upstream raw materials:

m-trifluoromethylphenyl iodide

2',3'-O-isopropylideneinosine

Downstream raw materials:

8-(3-trifluoromethylphenyl)inosine