2-amino-4,5-dibutoxybenzoic acid

Base Information

• Chemical Name: 2-amino-4,5-dibutoxybenzoic acid
• CAS No.: 1448460-84-1
• Molecular Formula: C₁₅H₂₃NO₄
• Molecular Weight: 281.352
• Mol file: 1448460-84-1.mol

Synonyms:2-amino-4,5-dibutoxybenzoic acid

Chemical Property of 2-amino-4,5-dibutoxybenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-4,5-dibutoxybenzoic acid

There total 4 articles about 2-amino-4,5-dibutoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 2-amino-4,5-dibutoxybenzoate (1448460-83-0) → 2-amino-4,5-dibutoxybenzoic acid (1448460-84-1)

Guidance literature:

With water; potassium hydroxide; In ethanol; Reflux;

DOI:10.1016/j.tet.2013.06.073

Reference yield:

methyl 3,4-dibutoxybenzoate → 2-amino-4,5-dibutoxybenzoic acid (1448460-84-1)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; nitric acid / 20 °C / Cooling with ice

2: tin(II) chloride dihdyrate; hydrogenchloride / ethanol / 20 °C

3: potassium hydroxide; water / ethanol / Reflux

With hydrogenchloride; tin(II) chloride dihdyrate; water; nitric acid; acetic acid; potassium hydroxide; In ethanol;

DOI:10.1016/j.tet.2013.06.073

Reference yield:

methyl 2-nitro-4,5-dibutoxybenzoate → 2-amino-4,5-dibutoxybenzoic acid (1448460-84-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tin(II) chloride dihdyrate; hydrogenchloride / ethanol / 20 °C

2: potassium hydroxide; water / ethanol / Reflux

With hydrogenchloride; tin(II) chloride dihdyrate; water; potassium hydroxide; In ethanol;

DOI:10.1016/j.tet.2013.06.073

upstream raw materials:

methyl 2-amino-4,5-dibutoxybenzoate

3,4-dihydroxybenzoic acid methyl ester