9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

Base Information

Chemical Name:9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine
CAS No.:1601689-31-9
Molecular Formula:C₂₇H₃₃N₃O₃
Molecular Weight:447.577
Hs Code.:

Synonyms:9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

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Technology Process of 9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

There total 2 articles about 9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1133-49-9
2,3,4-trimethoxybenzyl chloride

: 1601492-62-9
9-(piperazin-1-yl)-1,2,3,4-tetrahydroacridine

: 1601689-31-9
9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

Guidance literature:: With potassium carbonate; In chloroform; for 3h; Reflux;
DOI:10.1016/j.ejmech.2014.03.026

Reference yield:

: 5396-30-5
9-chloro-1,2,3,4-tetrahydroacridine

: 1601689-31-9
9-[4-(2,3,4-trimethoxybenzyl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine

Guidance literature:: Multi-step reaction with 2 steps

1: pentan-1-ol / 12 h / 140 °C / Sealed tube

2: potassium carbonate / chloroform / 3 h / Reflux

With potassium carbonate; In pentan-1-ol; chloroform;
DOI:10.1016/j.ejmech.2014.03.026