α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Base Information

Chemical Name:α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol
CAS No.:1289154-72-8
Molecular Formula:C₂₈H₂₆O₂
Molecular Weight:394.513
Hs Code.:

Synonyms:α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Suppliers and Price of α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

There total 4 articles about α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 938-16-9
2,2-dimethylpropiophenone

: 1289154-70-6
1-ethynyl-2-[(2-methoxyphenyl)ethynyl]benzene

: 1289154-72-8
α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Guidance literature:: 1-ethynyl-2-[(2-methoxyphenyl)ethynyl]benzene; With n-butyllithium; In diethyl ether; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

2,2-dimethylpropiophenone; In tetrahydrofuran; diethyl ether; hexane; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.3762/bjoc.7.58

Reference yield:

: 767-91-9
1-ethynyl-2-methoxybenzene

: 1289154-72-8
α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: copper(l) iodide; bis(triphenylphosphine)palladium(II) dichloride; triethylamine / toluene / 5 h / 70 °C

2.1: water; sodium hydroxide / methanol; diethyl ether / 0.5 h / 20 °C

3.1: n-butyllithium / diethyl ether; hexane / 0.5 h / 0 °C / Inert atmosphere

3.2: 3 h / 20 °C / Inert atmosphere

With copper(l) iodide; n-butyllithium; bis(triphenylphosphine)palladium(II) dichloride; water; triethylamine; sodium hydroxide; In methanol; diethyl ether; hexane; toluene; 1.1: Sonogashira reaction;
DOI:10.3762/bjoc.7.58

Reference yield:

: 1289154-68-2
({2-[(2-methoxyphenyl)ethynyl]phenyl}ethynyl)(trimethyl)silane

: 1289154-72-8
α-[[2-[(2-methoxyphenyl)ethynyl]phenyl]ethynyl]-α-(1,1-dimethylethyl)benzenemethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; sodium hydroxide / methanol; diethyl ether / 0.5 h / 20 °C

2.1: n-butyllithium / diethyl ether; hexane / 0.5 h / 0 °C / Inert atmosphere

2.2: 3 h / 20 °C / Inert atmosphere

With n-butyllithium; water; sodium hydroxide; In methanol; diethyl ether; hexane;
DOI:10.3762/bjoc.7.58