(R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

Base Information

Chemical Name:(R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide
CAS No.:889214-52-2
Molecular Formula:C₂₇H₄₀N₂O₆S
Molecular Weight:520.69
Hs Code.:

Synonyms:(R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

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Chemical Property of (R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

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Technology Process of (R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

There total 1 articles about (R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 889214-51-1
6-amino-4-benzylperhydro-1,4-thiazepin-5-one hydrochloride

: 270902-67-5
8,8-dimethyl-2-O-methyl-3,5-O-(1-methylethylidene)-6,7,8,9-tetradeoxy-D-gluo-6-nonenonic acid (6E)-γ-lactone

: 889214-52-2
(R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

Guidance literature:: With sodium 2-ethylhexanoic acid; In tetrahydrofuran; at 20 ℃; for 96h;

Reference yield: 49.0%

: 889214-52-2
(R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide

: N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-(E)-(2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8,8-dimethylnon-6-enamide

Guidance literature:: (R)-N-(4-benzyl-5-oxoperhydro-1,4-thiazepin-6-yl)-2-[(4R,5S,6R)-6-((E)-3,3-dimethylbut-1-enyl)-5-hydroxy-2,2-dimethyl-1,3-dioxinan-4-yl]-2-methoxyacetamide; With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 4h;

With sodium hydroxide; sodium chloride; In tetrahydrofuran; water; at 5 - 20 ℃; pH=7.0;