Technology Process of 4-((5-bromo-4-(mesityloxy)-6-oxo-1,6-dihydropyridin-2-yl)amino)benzonitrile
There total 7 articles about 4-((5-bromo-4-(mesityloxy)-6-oxo-1,6-dihydropyridin-2-yl)amino)benzonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium diacetate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate / 1,4-dioxane / 100 °C / Schlenk technique; Inert atmosphere
2: chloro-trimethyl-silane; sodium iodide / acetonitrile / Reflux
3: acetic acid; N-Bromosuccinimide; trifluoroacetic acid / 20 °C
With
N-Bromosuccinimide; chloro-trimethyl-silane; palladium diacetate; acetic acid; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; trifluoroacetic acid; sodium iodide; sodium t-butanolate;
In
1,4-dioxane; acetonitrile;
DOI:10.1016/j.bmc.2014.01.054
- Guidance literature:
-
Multi-step reaction with 2 steps
1: chloro-trimethyl-silane; sodium iodide / acetonitrile / Reflux
2: acetic acid; N-Bromosuccinimide; trifluoroacetic acid / 20 °C
With
N-Bromosuccinimide; chloro-trimethyl-silane; acetic acid; trifluoroacetic acid; sodium iodide;
In
acetonitrile;
DOI:10.1016/j.bmc.2014.01.054
