Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester

Base Information

• Chemical Name: Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester
• CAS No.: 94421-15-5
• Molecular Formula: C₁₉H₂₁NO₄S
• Molecular Weight: 359.446
• Mol file: 94421-15-5.mol

Synonyms:Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester

Chemical Property of Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester

There total 2 articles about Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

acetic anhydride (108-24-7) + 2-Nitro-1-phenyl-1-phenylsulfanyl-pentan-3-ol (94421-50-8) → Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester (94421-15-5)

Guidance literature:

With sulfuric acid;

DOI:10.1016/S0040-4039(01)81593-8

Reference yield:

(2-nitroethenyl)benzene (102-96-5) → Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester (94421-15-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / tetramethylguanidine / 24 h / Ambient temperature

2: 87 percent / H₂SO₄

With 1,1,3,3-tetramethylguanidine; sulfuric acid;

DOI:10.1016/S0040-4039(01)81593-8

Reference yield: 69.0%

Acetic acid 1-ethyl-2-nitro-3-phenyl-3-phenylsulfanyl-propyl ester (94421-15-5) → (E)-1-phenyl-1-penten-3-ol acetate (94421-30-4,113334-99-9,113334-98-8)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); at 80 ℃;

DOI:10.1016/S0040-4039(01)81593-8

upstream raw materials:

acetic anhydride

2-Nitro-1-phenyl-1-phenylsulfanyl-pentan-3-ol

(2-nitroethenyl)benzene

Downstream raw materials:

(E)-1-phenyl-1-penten-3-ol acetate