4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Base Information

• Chemical Name: 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole
• CAS No.: 1430730-39-4
• Molecular Formula: C₅₃H₄₇N₃O₉
• Molecular Weight: 869.971
• Mol file: 1430730-39-4.mol

Synonyms:4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Chemical Property of 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

There total 5 articles about 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)tetrazole (706784-62-5) + C18H20ClN → 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-39-4)

Guidance literature:

In m-xylene; for 3h; Reflux;

DOI:10.1016/j.ejmech.2014.02.041

Reference yield:

benzylamine (100-46-9) → 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-39-4)

Guidance literature:

Multi-step reaction with 3 steps

1: calcium chloride; triethylamine / 2 h / 0 - 20 °C

2: thionyl chloride / 2 h / Reflux

3: m-xylene / 3 h / Reflux

With thionyl chloride; triethylamine; calcium chloride; In m-xylene;

DOI:10.1016/j.ejmech.2014.02.041

Reference yield:

p-tert-butyl benzoyl chloride (1710-98-1) → 4-benzyl-5-(4-tert-butylphenyl)-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-39-4)

Guidance literature:

Multi-step reaction with 3 steps

1: calcium chloride; triethylamine / 2 h / 0 - 20 °C

2: thionyl chloride / 2 h / Reflux

3: m-xylene / 3 h / Reflux

With thionyl chloride; triethylamine; calcium chloride; In m-xylene;

DOI:10.1016/j.ejmech.2014.02.041

upstream raw materials:

p-tert-butyl benzoyl chloride

benzylamine

5-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)tetrazole

N-benzyl-4-(tert-butyl)benzamide

Downstream raw materials:

3-(4-tert-butylphenyl)-5-(β-D-glucopyranosyl)-1,2,4-triazole

4-benzyl-5-(β-D-glucopyranosyl)-3-(4-tert-butylphenyl)-1,2,4-triazole