3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester

Base Information

• Chemical Name: 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester
• CAS No.: 106787-68-2
• Molecular Formula: C₁₆H₁₉NO₆S
• Molecular Weight: 353.396
• Mol file: 106787-68-2.mol

Synonyms:3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester

Chemical Property of 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester

There total 4 articles about 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,O,O-Triacetyl-DL-dopamethylester (93023-12-2,106862-00-4) → 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester (106787-68-2)

Guidance literature:

With Lawessons reagent; In 1,2-dimethoxyethane; for 24h; Ambient temperature;

DOI:10.1248/cpb.34.1994

Reference yield:

N,O,O'-triacetyl-3,4-dihydroxyphenylalanine methyl ester (105760-25-6) → (S)-3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester (106787-68-2)

Guidance literature:

With Lawessons reagent; In 1,2-dimethoxyethane; for 24h; Ambient temperature;

DOI:10.1248/cpb.34.1994

Reference yield:

DL-3-(3,4-dihydroxyphenyl)alanine methyl ester hydrochloride (40611-00-5) → 3-(3,4-Diacetoxy-phenyl)-2-thioacetylamino-propionic acid methyl ester (106787-68-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 20 h / Ambient temperature

2: 90 percent / Lawesson's reagent / 1,2-dimethoxy-ethane / 24 h / Ambient temperature

With Lawessons reagent; pyridine; In 1,2-dimethoxyethane;

DOI:10.1248/cpb.34.1994

upstream raw materials:

N,O,O-Triacetyl-DL-dopamethylester

DL-3-(3,4-dihydroxyphenyl)alanine methyl ester hydrochloride

N,O,O'-triacetyl-3,4-dihydroxyphenylalanine methyl ester

L-dopa methyl ester hydrochloride

Downstream raw materials:

N-methylthiocarbonyl-3,4-dihydroxyphenylalanine methyl ester

(S)-N-methylthiocarbonyl-3,4-dihydroxyphenylalanine methyl ester

(S)-3,4-dihydroxyphenylalanine methyl ester hydroiodide

carboxymethyl-1 N-acetyl-2 (dihydroxy-3,4 phenyl)-3 alanine